ABBV-706

• Description :

  ABBV-706 is a SEZ6 targeting ADC, which is composed of the Linker-Payload conjugation (HY-148820) and the Anti-SEZ6 Antibody (SC17) (HY-P991041) . ABBV-706 exhibits high efficacy against small cell lung cancer (SCLC), neuroendocrine tumors (NENs) and central nervous system (CNS) tumors[1].

• UNSPSC :

  12352211

• Target :

  Antibody-Drug Conjugates (ADCs)

• Type :

  Reference compound

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/abbv-706.html

• Purity :

  99.71

• Smiles :

  [ABBV-706]

• References & Citations :

  [1]Chandana S R, et al. First-in-human study of ABBV-706, a seizure-related homolog protein 6 (SEZ6) –targeting antibody-drug conjugate (ADC), in patients (pts) with advanced solid tumors[J]. 2024.

• Shipping Conditions :

  Dry Ice

• Storage Conditions :

  -80°C, protect from light

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1