ABBV-154

CAT: 0804-HY-164893-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-164893-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ABBV-154 is an anti-TNF antibody-drug conjugate (ADC) . ABBV-154 is composed of the humanized antibody Adalimumab (HY-P9908) conjugated with a glucocorticoid receptor modulator (HY-137883) . ABBV-154 can be used in studies of rheumatoid arthritis, Crohn's disease and polymyalgia rheumatica[1].
UNSPSC
12352203
Target
Antibody-Drug Conjugates (ADCs) ; Glucocorticoid Receptor; TNF Receptor
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Apoptosis; Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/abbv-154.html
Smiles
[ABBV-154]
References & Citations
[1]Hobson AD, et al. Discovery of ABBV-154, an anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody-Drug Conjugate (iADC) . J Med Chem. 2023 Sep 14;66 (17) :12544-12558.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
Phase 2

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