ABBV-3373

• Description :

  ABBV-3373 is an anti-TNF antibody drug conjugate (ADC) . ABBV-3373 is composed of the humanized antibody Adalimumab (HY-P9908) conjugated with a glucocorticoid receptor modulator (HY-148436) . ABBV-3373 can be used in the study of rheumatoid arthritis[1].

• UNSPSC :

  12352203

• Target :

  Antibody-Drug Conjugates (ADCs) ; Glucocorticoid Receptor; TNF Receptor

• Type :

  Reference compound

• Related Pathways :

  Antibody-drug Conjugate/ADC Related; Apoptosis; Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/abbv-3373.html

• Purity :

  98.78

• Smiles :

  [ABBV-3373]

• References & Citations :

  [1]Qu P, et al. Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate. J Med Chem. 2022 Dec 8;65 (23) :15893-15934.

• Shipping Conditions :

  Dry Ice

• Storage Conditions :

  -80°C, protect from light

• Scientific Category :

  ADC Related

• Clinical Information :

  Phase 2