ABBV-467

CAT: 0804-HY-149672-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-149672-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
ABBV-467 is a selective MCL-1 inhibitor (Ki: apoptosis. ABBV-467 induces cancer cell death and inhibits tumor growth in models of hematological malignancies, such as multiple myeloma[1].
CAS Number
[2287186-66-5]
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/abbv-467.html
Purity
99.78
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)[C@@H](CC1=CC2=CC=C1OCC3=NC(C4=CC=C(OC[C@H]5OCCOC5)C=C4)=NC=C3)OC6=NC=NC7=C6C(C8=C(C)C(Cl)=C(O[C@@H](CO2)CN9CCN(C)CC9)C(Cl)=C8C)=C(C%10=CC=C(F)C=C%10)S7
Molecular Formula
C53H51Cl2FN6O9S
Molecular Weight
1037.98
References & Citations
[1]Yuda J, et al. Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients. Commun Med (Lond) . 2023 Oct 25;3 (1) :154.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Phase 1

Related Products

CatalogName
HY-W999587CRBN ligand-467
HY-164893-01ABBV-154
HY-146069-01ABBV-318
HY-156409-01ABBV-712
HY-112090-01ABBV-744
HY-142209-01ABBV-167
HY-163827ABBV-992
HY-164894-01ABBV-3373
HY-111757ABBV-4083
HY-170554-01ABBV-706

Alternative Products

CatalogName
MBS5824868ABBV-467
MBS131345Mivebresib (ABBV075, ABBV-075, ABBV 075)
T62000-01ABBV-318
T29517ABBV-221
T9901A-446-01ABBV-3373
T9901A-492-01ABBV-706
T10219ABBV-4083
MBS5824867ABBV-712
MBS5750765ABBV-744
T89551-01ABBV-992

Popular Products