RegisterLogin

TC-E 5005

CAT: 0804-HY-10568Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-10568Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
TC-E 5005 is a potent and selective PDE10A inhibitor with IC50 values of 7.28, 239, 779, 919, 3,100, and 3,700 nM for PDE10A, 2A, 11A, 5A, 7B and 3A, respectively. TC-E 5005 inhibits adrenergic and neurogenic smooth muscle contractions in the human prostate[1].
CAS Number
[959705-64-7]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/tc-e-5005.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C2C(N3C(C(C)=N2)=C(C)N=C3CCC)=N1
Molecular Formula
C15H18N4O
Molecular Weight
270.33
References & Citations
[1]Hennenberg M, et al. Inhibition of Adrenergic and Non-Adrenergic Smooth Muscle Contraction in the Human Prostate by the Phosphodiesterase 10-Selective Inhibitor TC-E 5005. Prostate. 2016 Nov;76 (15) :1364-74.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE10; PDE11; PDE2; PDE3; PDE5; PDE7

Related Products

CatalogName
HY-108516TC-E 5001
HY-110144TC-E 5008
HY-107574-01TC-E 5003
HY-163545Tc-Me2P
HY-107668ATC-1698
HY-124591-01TC-2153
HY-103462-01TC-F2
HY-172367Tc-BQ0413
HY-18159TC-6683
HY-W979493-01TC-2216

Alternative Products

CatalogName
MBS5757891TC-E 5005
M23780-01TC-E 5003
MBS3841617-01TC-E 5002
MBS387688-01TC-E 5006
256837-01TC-E 5007
T28932-01TC-E 5008
B5798-50TC-E 5001

Popular Products