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Tc-Me2P

CAT: 0804-HY-163545Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163545Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tc-Me2P is a 99MTC-labeled acrylamide (PnAO) derivative that contains two 4-methyl-2-nitroimidazole groups. The primary activity of Tc-Me2P is as an imaging agent for tumor hypoxia. By specifically binding to hypoxic regions in tumor tissue, it can be used for single photon emission computed tomography (SPECT) and positron emission tomography (PET) imaging to detect hypoxia in tumors. Tc-Me2P can be used to study the targeting of different chemical structures in tumors and normal tissues[1].
UNSPSC
12352005
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tc-me2p.html
Smiles
O=[Tc]123N4CCCN1C(C)(C)C(CN5C=C(C)N=C5[N+]([O-])=O)=[N]2O[H]O[N]3=C(CN6C=C(C)N=C6[N+]([O-])=O)C4(C)C
Molecular Formula
C21H31N10O7Tc
Molecular Weight
634.44
References & Citations
[1]Li S, et al. Preparation and bioevaluation of a novel 99mTc-labelled propylene amine oxime (PnAO) containing two 4-methyl-2-nitroimidazole groups as a promising tumor hypoxia imaging agent[J]. Bioorganic & Medicinal Chemistry Letters, 2024, 106: 129773.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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