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BMS-593214

CAT: 0804-HY-114511-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-114511-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMS-593214 is an active site-directed factor (F) VIIa inhibitor. BMS-593214 shows antithrombotic and antihaemostatic properties. BMS-593214 is a direct competitive inhibitor of human FVIIa and a non-competitive inhibitor of Viia-activated substrate FX. BMS-593214 prevents electroinduced carotid artery thrombosis (AT) and wire induced vena cava thrombosis (VT) [1].
CAS Number
1004551-40-9
Product Name Alternative
GNF-Pf-1127
UNSPSC
12352005
Target
Factor VIIa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bms-593214.html
Purity
99.90
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)C1=CC=C(C=C1)C2=CC(O)=C(C=C2[C@@H]3NC4=C([C@@]5([C@]3(CC6=C5C=CC=C6)[H])[H])C=C(C=C4)C(N)=N)OC
Molecular Formula
C31H27N3O4
Molecular Weight
505.56
References & Citations
[1]Wong PC, et al. BMS-593214, an active site-directed factor VIIa inhibitor: enzyme kinetics, antithrombotic and antihaemostatic studies. Thromb Haemost. 2010 Aug;104 (2) :261-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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