(Rac)-PDE4-IN-4

(Rac)-PDE4-IN-4

• UNSPSC Description: (Rac)-PDE4-IN-4 is the diastereomer mixture of PDE4-IN-4 (HY-115871). PDE4-IN-4 is a dual M3 (pIC50 = 10.2) antagonist-PDE4 (pIC50 = 8.8) inhibitor for the inhaled research of pulmonary diseases[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/rac-pde4-in-4.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CC=C(CNC(C2=CC=CC=C2)C(O[C@H]3CN4CCC3CC4)=O)S1)O[C@H](C5=CC=C(OC)C(OC)=C5)CC6=C(Cl)C=[N+]([O-])C=C6Cl
• Molecular Weight: 726.67
• References & Citations: [1]Armani E, et al. Discovery of M3 Antagonist-PDE4 Inhibitor Dual Pharmacology Molecules for the Treatment of Chronic Obstructive Pulmonary Disease. J Med Chem. 2021;64(13):9100-9119.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported