CDD-2110

CAT: 0804-HY-176884Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-176884Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDD-2210 is a STK33 inhibitor, with a Kd of 0.1 nM and an IC50 of 38 nM. CDD-2210 has relatively weak inhibitory effects on off-target kinases, with IC50 values of 1209 nM for CLK1, 917 nM for CLK2, 544 nM for CLK4, and 746 nM for RET. CDD-2210 can be used for the study of contraception[1].
CAS Number
[3086535-49-8]
Target
RET; STK33
Related Pathways
Cell Cycle/DNA Damage; Protein Tyrosine Kinase/RTK
Field of Research
Others
Smiles
O=C(N1CCC(C1)N2CCC(CC2)C(NC)=O)C3=CC4=C(NN=C4C#CC5=C(C6=CC=CC=C6)C=CC=C5)C=C3
Molecular Formula
C33H33N5O2
Molecular Weight
531.65
References & Citations
[1]Ku AF, et al. Reversible male contraception by targeted inhibition of serine/threonine kinase 33. Science. 2024 May 24;384 (6698) :885-890.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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