MTH1 degrader-1

• CAS Number:

  2412987-06-3

• UNSPSC Description:

  MTH1 degrader-1, a MTH1 aTAG inhibitor, is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). MTH1 degrader-1 can be used for synthesis PROTAC aTAG 4531 (HY-163168)[1].

• Target Antigen:

  DNA/RNA Synthesis; Ligands for Target Protein for PROTAC

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mth1-degrader-1.html

• Smiles:

  O=C(O)C1=CC=C(C2=C(F)C=C3N=CC(C(NC4CC4)=O)=C(NC5=CC=CC=C5)C3=C2)C=C1F

• Molecular Weight:

  459.44

• References & Citations:

  [1]Veits G K, et al. Development of an AchillesTAG degradation system and its application to control CAR-T activity. Current Research in Chemical Biology, 2021, 1: 100010.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported