MTH1 degrader-1

MTH1 degrader-1

• CAS Number: 2412987-06-3
• UNSPSC Description: MTH1 degrader-1, a MTH1 aTAG inhibitor, is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). MTH1 degrader-1 can be used for synthesis PROTAC aTAG 4531 (HY-163168)[1].
• Target Antigen: DNA/RNA Synthesis; Ligands for Target Protein for PROTAC
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mth1-degrader-1.html
• Smiles: O=C(O)C1=CC=C(C2=C(F)C=C3N=CC(C(NC4CC4)=O)=C(NC5=CC=CC=C5)C3=C2)C=C1F
• Molecular Weight: 459.44
• References & Citations: [1]Veits G K, et al. Development of an AchillesTAG degradation system and its application to control CAR-T activity. Current Research in Chemical Biology, 2021, 1: 100010.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported