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BMS-770767

CAT: 0804-HY-107124-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-107124-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMS-770767 is an 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor in type 2 diabetes. 11β-HSD1 is an important enzyme that is widely expressed in liver, adipose tissue and other tissues and plays an important role in metabolic diseases such as diabetes and obesity[1].
CAS Number
1875067-34-7
UNSPSC
12352005
Target
11β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bms-770767.html
Purity
99.90
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
OC12CC(CC2)(C3=NN=C4N3C=CC=C4OC5=C(C=CC=C5)Cl)CC1
Molecular Formula
C19H18ClN3O2
Molecular Weight
355.82
References & Citations
[1]Brad D Maxwell, et al. The synthesis and analysis of [phenyl-14 C (U) ]BMS-770767 and [13 C6 ]BMS-770767 for use in discovery biotransformation, human ADME and bioanalytical studies. J Labelled Comp Radiopharm. 2016 Dec;59 (14) :657-664.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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