Products for Research Use Only
RegisterLogin

Acetaminophen-13C6

CAT: 0804-HY-66005S3Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-66005S3Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Acetaminophen-13C6 (Paracetamol-13C6) is the 13C-labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].
CAS Number
2132405-57-1
Product Name Alternative
Paracetamol-13C6; 4-Acetamidophenol-13C6; 4'-Hydroxyacetanilide-13C6
UNSPSC
12352005
Target
COX; Endogenous Metabolite; Histone Acetyltransferase; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Epigenetics; Immunology/Inflammation; Metabolic Enzyme/Protease; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/acetaminophen-13c6.html
Solubility
10 mM in DMSO
Smiles
CC(N[13C]1=[13CH][13CH]=[13C]([13CH]=[13CH]1)O)=O
Molecular Formula
C2 13C6H9NO2
Molecular Weight
157.12
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Hinz, B, et al. Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. FASEB J, 2008. 22 (2) : p. 383-90.|[3]Miroslav Dinić, et al. Lactobacillus fermentum Postbiotic-induced Autophagy as Potential Approach for Treatment ofAcetaminophen Hepatotoxicity. Front Microbiol. 2017 Apr 6;8:594.|[4]Uchida NS, et al. Hepatoprotective Effect of Citral on Acetaminophen-Induced Liver Toxicity in Mice. Evid Based Complement Alternat Med. 2017;2017:1796209.|[5]Rothen JP, et al. Acetaminophen is an inhibitor of hepatic N-acetyltransferase 2 in vitro and in vivo. Pharmacogenetics. 1998 Dec;8 (6) :553-9.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-66005S4-01Acetaminophen-13C2,15N
HY-66005-01Acetaminophen
HY-G0004-01Acetaminophen metabolite 3-hydroxy-acetaminophen
HY-G0004R-01Acetaminophen metabolite 3-hydroxy-acetaminophen (Standard)
HY-66005S5Acetaminophen-d5
HY-66005S1-01Acetaminophen-d3
HY-113083Acetaminophen glucuronide
HY-66005S2-01Acetaminophen-d7
HY-138128Acetaminophen mercapturate
HY-66005S-01Acetaminophen-d4

Alternative Products

CatalogName
BUP18863-01Acetaminophen
001108Acetaminophen Acetate (Acetaminophen Impurity)

Popular Products