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USP1-IN-7

CAT: 0804-HY-161446-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-161446-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
USP1-IN-7 (Compound 3) is an inhibitor for ubiquitin specific peptidase 1 (USP1) and its cofactor UAF1, with IC50 ≤50 nM. USP1-IN-7 inhibits proliferation of MDA-MB-436 with IC50 ≤50 nM[1].
CAS Number
3033480-42-8
UNSPSC
12352005
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/usp1-in-7.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN(C1=CN=C(C(F)=C1N2CC3=CC=C(C4=NC(C(F)(F)F)=CN4C)C=C3)C5=C(OC)N=CN=C5C6CC6)C2=O
Molecular Formula
C27H23F4N7O2
Molecular Weight
553.51
References & Citations
[1]Liu BM, et al., Carbonyl fused heterocyclic derivative used as ubiquitin-specific protease inhibitor. WO2024061213A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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