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USP1-IN-15

CAT: 0013-GTR19274503-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274503-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
USP1-IN-15 is an orally effective and selective inhibitor of USP1 with an IC50 of 12.3 nM. It demonstrates high specificity towards USP1, with negligible inhibition of off-target deubiquitinating enzymes. USP1-IN-15 blocks cell colony formation, induces S phase arrest, and stabilizes ubiquitinated PCNA. Additionally, USP1-IN-15 exhibits synergistic antiproliferative activity and significantly inhibits tumor growth in vivo. This compound can be utilized for research on BRCA-mutated breast cancer.
Storage Conditions
-20°C
Notes
For research use only.

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