USP1-IN-14

• Description:

  USP1-IN-14 (compound 27) is a ubiquitin-specific protease 1 (USP1) inhibitor with an IC50 of 0.001 µM. USP1-IN-14 can be used for USP1-related cancers, autoimmune and inflammatory disorders research[1].

• UNSPSC:

  12352005

• Target:

  Deubiquitinase

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Cancer; Inflammation/Immunology

• Smiles:

  COC1=C(C2=NC(C=CC=N3)=C3C(O[C@@H](C4=CC=C(C5=NC(C(F)(F)F)=CN5C(C)C)C=C4)C)=N2)C(C6CC6)=NC=N1

• Molecular Formula:

  C30H28F3N7O2

• Molecular Weight:

  575.58

• References & Citations:

  [1]Hoyle DE, et al. Design and Synthesis of Novel USP1 Inhibitors for Therapeutic Applications. ACS Med Chem Lett. 2025 Oct 30;16 (11) :2197-2199.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  USP1

• CAS Number:

  [3084277-96-0]