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USP1-IN-2

CAT: 0804-HY-148099-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-148099-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
USP1-IN-2 (Compound I-193) is a potent ubiquitin-specific protease 1 (USP1) inhibitor with an IC50 of less than about 50 nM. USP1-IN-2 can be used for the study of cancers such as osteosarcoma[1].
CAS Number
2098212-05-4
UNSPSC
12352005
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/usp1-in-2.html
Purity
99.76
Solubility
DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1NC2=CN=C(C3=C(C(C)C)C(F)=CC=C3)N=C2N1CC4=CC=C(C5=NC(C(F)(F)F)=CN5C)C=C4
Molecular Formula
C26H22F4N6O
Molecular Weight
510.49
References & Citations
[1]Alexandre Joseph Buckmelter, et al. Purinones as ubiquitin-specific protease 1 inhibitors. Patent US20170145012A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
USP1

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