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USP1-IN-4

CAT: 0804-HY-153731Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-153731Size:1 Each
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Description
USP1-IN-4 (compound 10) is an effective USP1 inhibitor with an IC50 value of 2.44 nM. USP1-IN-4 has anticancer activity and synergistic activity with various anticancer drugs[1].
CAS Number
2878441-72-4
UNSPSC
12352005
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/usp1-in-4.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C1=CN(C)C(C2=CC=C(CC3=NC=C4C=NC(C5=C(C(C)C)C=CC=C5)=NN43)C=C2)=N1)F
Molecular Formula
C26H23F3N6
Molecular Weight
476.50
References & Citations
[1]Cai S, et al. Nitrogen-containing fused heteroaromatic bicyclic compounds as USP1 inhibitors and the use thereof. China, WO 2022/253188 A.2022-8-12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
USP1

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