Myosin modulator 1

• UNSPSC Description:

  Myosin modulator 1 (Compound B141) is a modulator for myosin, that inhibits ATPase in rabbits psoas, porcine atria and in porcine ventricle, with IC25s of 0.42, 0.13 and 3.09 μM, respectively. Myosin modulator 1 regulates systolic cardiac performance in Sprague Dawley rats[1].

• Target Antigen:

  Myosin

• Type:

  Reference compound

• Related Pathways:

  Cytoskeleton

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/myosin-modulator-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N(CC(N[C@@H](C1=NC=C(C#N)C=C1F)C)=O)C2)NC3=C2C(F)=C(F)C=C3

• Molecular Weight:

  389.33

• References & Citations:

  [1]Hawryluk N, et al., 1,4-dihydroquinazolinone compounds and uses thereof. WO2024073426A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3034189-56-2