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Myosin modulator 1

CAT: 0804-HY-161608Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161608Size:1 Each
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Description
Myosin modulator 1 (Compound B141) is a modulator for myosin, that inhibits ATPase in rabbits psoas, porcine atria and in porcine ventricle, with IC25s of 0.42, 0.13 and 3.09 μM, respectively. Myosin modulator 1 regulates systolic cardiac performance in Sprague Dawley rats[1].
CAS Number
3034189-56-2
UNSPSC
12352005
Target
Myosin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/myosin-modulator-1.html
Solubility
10 mM in DMSO
Smiles
O=C(N(CC(N[C@@H](C1=NC=C(C#N)C=C1F)C)=O)C2)NC3=C2C(F)=C(F)C=C3
Molecular Formula
C18H14F3N5O2
Molecular Weight
389.33
References & Citations
[1]Hawryluk N, et al., 1,4-dihydroquinazolinone compounds and uses thereof. WO2024073426A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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