Myosin modulator 2

• Description:

  Myosin modulator 2 (Compound B172) is a modulator for myosin, that inhibits ATPase in rabbits psoas, porcine atria and in porcine ventricle, with IC25s of 2.013, 2.94 and 20.93 μM, respectively. Myosin modulator 2 regulates systolic cardiac performance in Sprague Dawley rats[1].

• UNSPSC:

  12352005

• Target:

  Myosin

• Type:

  Reference compound

• Related Pathways:

  Cytoskeleton

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/myosin-modulator-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1NC2=CC=C (F) C=C2CN1CC (N[C@H] (C3=NC=C (C#N) C=C3) C) =O

• Molecular Formula:

  C18H16FN5O2

• Molecular Weight:

  353.35

• References & Citations:

  [1]Hawryluk N, et al., 1,4-dihydroquinazolinone compounds and uses thereof. WO2024073426A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  3034189-87-9