P-MPPF

• Description :

  P-MPPF is a selective 5-HT antagonist that dose-dependently antagonizes the reduction of phosphorylated Erk1/2 levels in the hippocampus induced by 8-OH-DPAT (HY-112061) in rats. p-MPPF can be used for neurological disease research[1].

• CAS Number :

  [155204-26-5]

• UNSPSC :

  12352005

• Target :

  5-HT Receptor; PERK

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/p-mppf.html

• Smiles :

  O=C(N(CCN1CCN(C2=CC=CC=C2OC)CC1)C3=NC=CC=C3)C4=CC=C(F)C=C4

• Molecular Formula :

  C25H27FN4O2

• Molecular Weight :

  434.51

• References & Citations :

  [1]Chen J, et al. 5-HT1A receptor-mediated regulation of mitogen-activated protein kinase phosphorylation in rat brain. Eur J Pharmacol. 2002 Oct 4;452 (2) :155-62.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported