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P-MPPF

CAT: 0804-HY-137111A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-137111A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
P-MPPF is a selective 5-HT antagonist that dose-dependently antagonizes the reduction of phosphorylated Erk1/2 levels in the hippocampus induced by 8-OH-DPAT in rats. p-MPPF can be used for neurological disease research[1].
CAS Number
155204-26-5
UNSPSC
12352005
Target
5-HT Receptor; PERK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/p-mppf.html
Smiles
O=C(N(CCN1CCN(C2=CC=CC=C2OC)CC1)C3=NC=CC=C3)C4=CC=C(F)C=C4
Molecular Formula
C25H27FN4O2
Molecular Weight
434.51
References & Citations
[1]Chen J, et al. 5-HT1A receptor-mediated regulation of mitogen-activated protein kinase phosphorylation in rat brain. Eur J Pharmacol. 2002 Oct 4;452 (2) :155-62.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported