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P, p'-DDD (Standard)

CAT: 0804-HY-B1984R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1984R-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
P, p'-DDD (Standard) is the analytical standard of p, p'-DDD. This product is intended for research and analytical applications. p, p'-DDD (4,4’-DDD) is an organochlorine insecticide, a major metabolite of p, p'-DDT. p, p'-DDD is an agonist at estrogen receptor α (ERα) and ERβ. p, p'-DDD increases DNA damage, apoptosis and necrosis in peripheral blood. p, p'-DDD stimulates cell proliferation in SKBR3 cells. p, p'-DDD activates the AP-1 transcription factor. p, p'-DDD decreases sleep times of barbiturates and steroids in rats.
CAS Number
72-54-8
Product Name Alternative
4,4'-DDD (Standard) ; p, p'-Dichlorodiphenyl dichloroethane (Standard)
UNSPSC
12352005
Target
Apoptosis; Drug Metabolite; Insecticide; Necroptosis; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Field of Research
Cancer; Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/p-p-ddd-standard.html
Smiles
ClC(Cl)C(C1=CC=C(Cl)C=C1)C2=CC=C(Cl)C=C2
Molecular Formula
C14H10Cl4
Molecular Weight
320.04
References & Citations
[1]Mendel JL, et al. Conversion of p, p' -DDT to p, p' -DDD by intestinal flora of the rat. Science. 1966;151 (3717) :1527-1528.|[2]Gerić M, et al. Cytogenetic status of human lymphocytes after exposure to low concentrations of p, p'-DDT, and its metabolites (p, p'-DDE, and p, p'-DDD) in vitro. Chemosphere. 2012;87 (11) :1288-1294.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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