p,p'-DDE (Standard)
CAT:
804-HY-B1986R
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
p,p'-DDE (Standard)
- CAS Number: 72-55-9
- UNSPSC Description: p,p'-DDE (Standard) is the analytical standard of p,p'-DDE. This product is intended for research and analytical applications. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM[1].
- Target Antigen: Androgen Receptor; Drug Metabolite
- Type: Reference Standards
- Related Pathways: Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
- Field of Research: Endocrinology
- Assay Protocol: https://www.medchemexpress.com/p-p-dde-standard.html
- Smiles: Cl/C(Cl)=C(C1=CC=C(Cl)C=C1)/C2=CC=C(Cl)C=C2
- Molecular Weight: 318.03
- References & Citations: [1]Kelce WR, et al. Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist. Nature. 1995;375(6532):581-585.
- Shipping Conditions: Room temperature