p,p'-DDE (Standard)

p,p'-DDE (Standard)

• CAS Number: 72-55-9
• UNSPSC Description: p,p'-DDE (Standard) is the analytical standard of p,p'-DDE. This product is intended for research and analytical applications. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM[1].
• Target Antigen: Androgen Receptor; Drug Metabolite
• Type: Reference Standards
• Related Pathways: Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
• Field of Research: Endocrinology
• Assay Protocol: https://www.medchemexpress.com/p-p-dde-standard.html
• Smiles: Cl/C(Cl)=C(C1=CC=C(Cl)C=C1)/C2=CC=C(Cl)C=C2
• Molecular Weight: 318.03
• References & Citations: [1]Kelce WR, et al. Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist. Nature. 1995;375(6532):581-585.
• Shipping Conditions: Room temperature