p,p'-DDE (Standard)

• CAS Number:

  72-55-9

• UNSPSC Description:

  p,p'-DDE (Standard) is the analytical standard of p,p'-DDE. This product is intended for research and analytical applications. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM[1].

• Target Antigen:

  Androgen Receptor; Drug Metabolite

• Type:

  Reference Standards

• Related Pathways:

  Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

• Field of Research:

  Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/p-p-dde-standard.html

• Smiles:

  Cl/C(Cl)=C(C1=CC=C(Cl)C=C1)/C2=CC=C(Cl)C=C2

• Molecular Weight:

  318.03

• References & Citations:

  [1]Kelce WR, et al. Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist. Nature. 1995;375(6532):581-585.

• Shipping Conditions:

  Room temperature