Products for Research Use Only
RegisterLogin

STING agonist-38

CAT: 0804-HY-158711Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-158711Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
STING agonist-38 (compound 58) is a potent agonist of STING, with the EC50 of 0.05 μM in THP1 cells. STING agonist-38 has certain oral bioactivity[1].
CAS Number
2850251-27-1
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sting-agonist-38.html
Smiles
O=C(C1=CC2=C(C(OC)=C1)N(CCCNC3=NC=C(C4=C(C(F)(F)F)C=CC=C4)O3)C(NC(C5=CC(C)=NN5CC)=O)=N2)N
Molecular Formula
C29H29F3N8O4
Molecular Weight
610.59
References & Citations
[1]China Pharmaceutical University. Preparation of benzimidazole compounds for treatment of STING protein function related diseases. China, CN115141182 A 2022-10-04
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

STING Agonist D61
CAS Number2850251-27-1
PubChem CID170915531
IUPAC Name2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxy-1-[3-[[5-[2-(trifluoromethyl)phenyl]-1,3-oxazol-2-yl]amino]propyl]benzimidazole-5-carboxamide
Molecular FormulaC29H29F3N8O4
Molecular Weight610.6
XLogP4.1
Topological Polar Surface Area155
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count11
Rotatable Bond Count11
Heavy Atom Count44
Formal Charge0
Complexity995
SMILES
CCN1C(=CC(=N1)C)C(=O)NC2=NC3=C(N2CCCNC4=NC=C(O4)C5=CC=CC=C5C(F)(F)F)C(=CC(=C3)C(=O)N)OC
InChI
InChI=1S/C29H29F3N8O4/c1-4-40-21(12-16(2)38-40)26(42)37-27-36-20-13-17(25(33)41)14-22(43-3)24(20)39(27)11-7-10-34-28-35-15-23(44-28)18-8-5-6-9-19(18)29(30,31)32/h5-6,8-9,12-15H,4,7,10-11H2,1-3H3,(H2,33,41)(H,34,35)(H,36,37,42)
InChIKey
SAIPDXPIJPBWOT-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of STING Agonist D61
CAS: 2850251-27-1
CID: 170915531
Formula: C29H29F3N8O4
MW: 610.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight610.6
XLogP34.1
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count11
Rotatable Bond Count11
Exact Mass610.22638592
Monoisotopic Mass610.22638592
Topological Polar Surface Area155 Ų
Heavy Atom Count44
Formal Charge0
Complexity995
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-150074STING agonist-18
HY-152958STING agonist-25
HY-152960STING agonist-27
HY-144328STING agonist-10
HY-152956-01STING agonist-23
HY-147834STING agonist-9
HY-139179-01STING agonist-14
HY-143896-01STING agonist-7
HY-178966STING agonist-48
HY-177338STING agonist-45

Alternative Products

CatalogName
463304STING Agonist 12b
T207376-01STING agonist-42
T72688-01STING agonist-20
T63457-01STING agonist-10
T83841-01STING Agonist D61
T13014-01STING agonist-3
T75093-01STING agonist-25
T74268-01STING agonist-13
B2047-5STING AGONIST G10
MBS3611610-01STING agonist-1

Popular Products