DAPD-NHc-pr

• Description :

  DAPD-NHc-pr (compound 12) is an HIV inhibitor with EC50/EC90 values of 0.85 μM and 13 μM, respectively. DAPD-NHc-pr shows no toxicity to normal cells (PBM, CEM, VERO) [1].

• UNSPSC :

  12352005

• Target :

  HIV

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/dapd-nhc-pr.html

• Smiles :

  NC1=NC(NC2CC2)=C3N=CN([C@@H]4O[C@H](CO)OC4)C3=N1

• Molecular Formula :

  C12H16N6O3

• Molecular Weight :

  292.29

• References & Citations :

  [1]Narayanasamy J, et al. Synthesis and anti-HIV activity of (-) -beta-D- (2R,4R) -1,3-dioxolane-2,6-diamino purine (DAPD) (amdoxovir) and (-) -beta-D- (2R,4R) -1,3-dioxolane guanosine (DXG) prodrugs. Antiviral Res. 2007 Sep;75 (3) :198-209.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [280138-71-8]