DAPD-NHc-pr

CAT: 0804-HY-117105Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-117105Size:1 Each

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Description

DAPD-NHc-pr (compound 12) is an HIV inhibitor with EC50/EC90 values of 0.85 μM and 13 μM, respectively. DAPD-NHc-pr shows no toxicity to normal cells (PBM, CEM, VERO) [1].

CAS Number

280138-71-8

UNSPSC

12352005

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dapd-nhc-pr.html

Smiles

NC1=NC(NC2CC2)=C3N=CN([C@@H]4O[C@H](CO)OC4)C3=N1

Molecular Formula

C12H16N6O3

Molecular Weight

292.29

References & Citations

[1]Narayanasamy J, et al. Synthesis and anti-HIV activity of (-) -beta-D- (2R,4R) -1,3-dioxolane-2,6-diamino purine (DAPD) (amdoxovir) and (-) -beta-D- (2R,4R) -1,3-dioxolane guanosine (DXG) prodrugs. Antiviral Res. 2007 Sep;75 (3) :198-209.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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