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NHC-diphosphate

CAT: 0931-T36880-01Size: 1 mgDry Ice: NoHazardous: No
CAT#: T36880-01Size: 1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
39023-73-9
Target
HCV Protease|||Others|||SARS-CoV|||Endogenous Metabolite|||Topoisomerase|||Virus Protease
Related Pathways
Metabolism|||Proteases/Proteasome|||Microbiology/Virology|||Others|||DNA Damage/DNA Repair
Bioactivity
NHC-diphosphate, a phosphorylated intracellular metabolite of ?-d-N4-Hydroxycytidine (NHC) in its diphosphate form[1], serves as a potent antiviral agent. As a pyrimidine ribonucleoside, NHC effectively counters the replication of Venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV), and hepatitis C virus (HCV) [1].
Smiles
ON=c1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)[nH]1
Molecular Formula
C9H15N3O12P2
Molecular Weight
419.18
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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