AChE-IN-91

• Description:

  AChE-IN-91 (Compound 8u) is a AChE inhibitor with an IC50 of 0.05 μM. AChE-IN-91 has significant anticholinesterase activity, promising for neurological diseases like Alzheimer's disease (AD) research[1].

• UNSPSC:

  12352005

• Target:

  Cholinesterase (ChE)

• Related Pathways:

  Neuronal Signaling

• Field of Research:

  Neurological Disease

• Smiles:

  ClC1=CC=C (C=C1) C2NC (NC (C) =C2C3=NC (C4=CC=C (C=C4) F) =NO3) =O

• Molecular Formula:

  C19H14ClFN4O2

• Molecular Weight:

  384.79

• References & Citations:

  [1]Ambatwar R, et al. Synthesis and evaluation of novel dihydropyrimidine-oxadiazole hybrid scaffolds as anticholinesterase agents: SAR and in-silico studies. Bioorg Med Chem Lett. 2025 Jul 4;128:130327.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  AChE

• CAS Number:

  1171708-92-1