PT-88

CAT: 0931-T88090-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T88090-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2803307-04-0
Target
MTOR
Related Pathways
PI3K/Akt/mTOR signaling
Bioactivity
PT-88, a highly selective mTOR (Mammalian target of rapamycin) inhibitor (IC 50 =1.2 nM), effectively targets both mTORC1 and mTORC2 complexes. These complexes represent the active isoforms of mTOR protein kinases, integral to cell growth, proliferation, and survival. The utility of PT-88 extends to researching mTOR's involvement in tumorigenesis and development, with significant applications in breast cancer treatments.
Smiles
O=C1OCC2=CC(=CC=C12)NC(=O)NC=3C=CC(=CC3)C=4N=C(N=C(N4)N5C6COCC5CC6)N7C8COCC7CC8
Molecular Formula
C30H31N7O5
Molecular Weight
569.61
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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