PT-88

• Target :

  MTOR

• Related Pathways :

  PI3K/Akt/mTOR signaling

• Bioactivity :

  PT-88, a highly selective mTOR (Mammalian target of rapamycin) inhibitor (IC 50 =1.2 nM), effectively targets both mTORC1 and mTORC2 complexes. These complexes represent the active isoforms of mTOR protein kinases, integral to cell growth, proliferation, and survival. The utility of PT-88 extends to researching mTOR's involvement in tumorigenesis and development, with significant applications in breast cancer treatments.

• Smiles :

  O=C1OCC2=CC(=CC=C12)NC(=O)NC=3C=CC(=CC3)C=4N=C(N=C(N4)N5C6COCC5CC6)N7C8COCC7CC8

• Molecular Formula :

  C30H31N7O5

• Molecular Weight :

  569.61

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2803307-04-0