U-89360E

• Description :

  U-89360E is an inhibitor for HIV-1 protease. U-89360E inhibits the protease of HIV-1 wildtype, V82D mutant and V82N mutant with Ki of 20 nM, 560 nM and 2100 nM, respectively[1].

• UNSPSC :

  12352211

• Target :

  HIV; HIV Protease

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/u-89360e.html

• Smiles :

  N=C(N)NCCC[C@@H](C(N)=O)NC([C@H](CCC(N)=O)NC([C@H](C(C)C)C[C@H](O)[C@@H](NC(C)=O)CC1CCCCC1)=O)=O

• Molecular Formula :

  C28H52N8O6

• Molecular Weight :

  596.76

• References & Citations :

  [1]Hong L, et al., Crystal structures of complexes of a peptidic inhibitor with wild-type and two mutant HIV-1 proteases. Biochemistry. 1996 Aug 20;35 (33) :10627-33.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [161897-65-0]