MAP3K2 rabbit pAb

• Background:

  The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq, Jul 2008]

• Description:

  The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq, Jul 2008],

• UniProt:

  Q9Y2U5

• Swiss Prot:

  Q9Y2U5

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from human MAP3K2 AA range: 220-300

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:1000-2000 ELISA 1:5000-20000

• Storage Conditions:

  -20°C/1 year

• Fragment:

  IgG

• Subcellular Location:

  Cytoplasm . Nucleus . Upon EGF stimulation, translocates into the nucleus.

• Other Product Names:

  Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25; MAPK/ERK kinase kinase 2; MEK kinase 2; MEKK 2)

• Gene ID (Human):

  10746