JAK2 Rabbit rabbit pAb

• Background:

  This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008]

• Description:

  This gene product is a protein tyrosine kinase involved in a specific subset of Cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008],

• Synonyms:

  Tyrosine-protein kinase JAK2 (EC 2.7.10.2;Janus kinase 2;JAK-2)

• Gene ID:

  3717

• UniProt:

  O60674

• Cellular Locus:

  Endomembrane system ; Peripheral membrane protein. Cytoplasm. Nucleus.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant Protein of JAK2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  IHC, IF

• Validated Applications:

  IHC, IF

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  IHC-p 1:50-300

• Molecular Weight:

  120kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  120 kD

• Subcellular Location:

  Endomembrane system ; Peripheral membrane protein . Cytoplasm . Nucleus .

• Other Product Names:

  Tyrosine-protein kinase JAK2 (EC 2.7.10.2; Janus kinase 2; JAK-2)

• Gene ID (Human):

  3717

• SwissProt (Human):

  O60674