FLT3/HDAC-IN-2

• UNSPSC Description:

  FLT3/HDAC-IN-2 is (compound 25h) a FLT3/HDAC dual inhibitor. FLT3/HDAC-IN-2 has antiproliferative activity against MOLM-13 cells. FLT3/HDAC-IN-2 can be used in acute myeloid leukemia research[1].

• Target Antigen:

  FLT3; HDAC

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Epigenetics;Protein Tyrosine Kinase/RTK

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/flt3-hdac-in-2.html

• Smiles:

  NC(C1=C(NC2=CC=C(N3CCN(CCCCCCCC(NO)=O)CC3)C(OC)=C2)N=C(NC4CCOCC4)C(CC)=N1)=O

• Molecular Weight:

  612.76

• References & Citations:

  [1]Chang Y, et al. Simultaneous inhibition of FLT3 and HDAC by novel 6-ethylpyrazine-2-Carboxamide derivatives provides therapeutic advantages in acute myelocytic leukemia. Eur J Med Chem. 2024 Sep 6;279:116847.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported