Products for Research Use Only
RegisterLogin

SD-70

CAT: 0804-HY-121522-03Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-121522-03Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SD-70 is an inhibitor for histone demethylase JMJD2C and exhibits antitumor efficacy. SD-70 inhibits viability of cancer cells CWR22Rv1 (9% cell survival at 10 μM), PC3 (14% cell survival at 2 μM) and DU145 (26% cell survival at 2 μM) [1].
CAS Number
332173-89-4
UNSPSC
12352005
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sd-70.html
Purity
99.20
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)C(NC(C1=CC=CO1)C2=CC=C3C=CC=NC3=C2O)=O
Molecular Formula
C18H18N2O3
Molecular Weight
310.35
References & Citations
[1]Xie M, et al., Inhibitors of jmjd2c as anticancer agents. WO2015167874.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

N-[2-furanyl-(8-hydroxy-7-quinolinyl)methyl]-2-methylpropanamide

N-[2-furanyl-(8-hydroxy-7-quinolinyl)methyl]-2-methylpropanamide is a hydroxyquinoline.

CAS Number332173-89-4
PubChem CID2876959
IUPAC NameN-[furan-2-yl-(8-hydroxyquinolin-7-yl)methyl]-2-methylpropanamide
Molecular FormulaC18H18N2O3
Molecular Weight310.3
XLogP3.3
Topological Polar Surface Area75.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count23
Formal Charge0
Complexity415
SMILES
CC(C)C(=O)NC(C1=C(C2=C(C=CC=N2)C=C1)O)C3=CC=CO3
InChI
InChI=1S/C18H18N2O3/c1-11(2)18(22)20-16(14-6-4-10-23-14)13-8-7-12-5-3-9-19-15(12)17(13)21/h3-11,16,21H,1-2H3,(H,20,22)
InChIKey
PBZYAPZLINAHET-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-[2-furanyl-(8-hydroxy-7-quinolinyl)methyl]-2-methylpropanamide
CAS: 332173-89-4
CID: 2876959
Formula: C18H18N2O3
MW: 310.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight310.3
XLogP33.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass310.13174244
Monoisotopic Mass310.13174244
Topological Polar Surface Area75.4 Ų
Heavy Atom Count23
Formal Charge0
Complexity415
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-167092SD-1077
HY-172946SD-2301
HY-129602-01SD-36
HY-W015445-01SD-169
HY-108019SD 8381
HY-164525SD-7300
HY-13227-01SD-208
HY-169360-01SD-436
HY-112391SD-1029
HY-149212-01SD-6

Alternative Products

CatalogName
GTR19236425-01SD-70
MBS131434SD-208 (SD 208; SD208)
M33557-01SD-36
A4515-10SD 1008
C5850-10SD 169
T7661-01SD-169
T7276-01SD 0006
T73575-01SD-6
MBS386152-01SD-208
574875SD-1008

Popular Products