SD-70

• Description :

  SD-70 is an inhibitor for histone demethylase JMJD2C and exhibits antitumor efficacy. SD-70 inhibits viability of cancer cells CWR22Rv1 (9% cell survival at 10 μM), PC3 (14% cell survival at 2 μM) and DU145 (26% cell survival at 2 μM) [1].

• UNSPSC :

  12352005

• Target :

  Histone Demethylase

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/sd-70.html

• Purity :

  99.20

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  CC(C)C(NC(C1=CC=CO1)C2=CC=C3C=CC=NC3=C2O)=O

• Molecular Formula :

  C18H18N2O3

• Molecular Weight :

  310.35

• References & Citations :

  [1]Xie M, et al., Inhibitors of jmjd2c as anticancer agents. WO2015167874.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [332173-89-4]