SD-70

• Description:

  SD-70 is an inhibitor for histone demethylase JMJD2C and exhibits antitumor efficacy. SD-70 inhibits viability of cancer cells CWR22Rv1 (9% cell survival at 10 μM), PC3 (14% cell survival at 2 μM) and DU145 (26% cell survival at 2 μM) [1].

• UNSPSC:

  12352005

• Target:

  Histone Demethylase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/sd-70.html

• Purity:

  99.20

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC(C)C(NC(C1=CC=CO1)C2=CC=C3C=CC=NC3=C2O)=O

• Molecular Formula:

  C18H18N2O3

• Molecular Weight:

  310.35

• References & Citations:

  [1]Xie M, et al., Inhibitors of jmjd2c as anticancer agents. WO2015167874.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [332173-89-4]