PRMT5-IN-29

• Description :

  PRMT5-IN-29 is a potent and orally active PRMT5 Inhibitor with an IC50 of 1.5 μΜ. PRMT5-IN-29 has the potential for advanced cancers research[1].

• UNSPSC :

  12352005

• Target :

  Histone Methyltransferase

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/prmt5-in-29.html

• Purity :

  98.01

• Solubility :

  DMSO : 130 mg/mL (ultrasonic)

• Smiles :

  O[C@H]([C@@H]1O)[C@@H](O[C@]1([H])[C@](O)(C(C=C2)=CC(Cl)=C2Cl)C)N3C(NC=N/C4=N\OC)=C4N=C3.Cl

• Molecular Formula :

  C18H20Cl3N5O5

• Molecular Weight :

  492.74

• References & Citations :

  [1]Liang Lu, et al. Brm targeting compounds and associated methods of use. Patent WO2023287787A1.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2242788-69-6]