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CB2R/FAAH modulator-3

CAT: 0804-HY-152254-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-152254-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CB2R/FAAH modulator-3 (compound 27) is a dual targeting modulator that acts as a CB2R agonist and FAAH inhibitor. The Ki values for CB2R/FAAH modulator-3 are 20.1 and 67.6 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 3.4 μM. CB2R/FAAH modulator-3 can be used in studies related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection[1].
CAS Number
2876918-67-9
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Cannabinoid Receptor; FAAH
Type
Reference compound
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cb2r-faah-modulator-3.html
Purity
99.71
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=C(OCCCCC)C=CC=C1)N[C@@]2(C3)CC4CC3CC(C4)C2
Molecular Formula
C22H31NO2
Molecular Weight
341.49
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Francesca Intranuovo, et al. Development of N- (1-Adamantyl) benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase. J Med Chem. 2023 Jan 12;66 (1) :235-250.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CB1; CB2

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