CB2R-IN-1

• Description:

  CB2R-IN-1 is a potent cannabinoid CB2 receptor inverse agonist with a Ki of 0.9 nM.

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  Cannabinoid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/CB2R-IN-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=S (C (F) (F) F) (NCC1 (CCC) CCN (S (=O) (C (N2S (=O) (C3=NC=CC=C3) =O) =CC4=C2C=CC=C4) =O) CC1) =O

• Molecular Formula:

  C23H27F3N4O6S3

• Molecular Weight:

  608.67

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Tong L, et al. Expansion of SAR studies on triaryl bis sulfone cannabinoid CB2 receptor ligands. Bioorg Med Chem Lett. 2010 Nov 15;20 (22) :6785-9.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CB2

• CAS Number:

  1257555-79-5