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CB2R agonist 1

CAT: 0804-HY-152576Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-152576Size:1 Each
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Description
CB2R agonist 1 is a selective ligand of cannabinoid receptor subtype 2 (CB2R) with an EC50 value of 0.56 µM. CB2R agonist 1 has high affinity and excellent selectivity for human CB2R and CB1R respectively. CB2R agonist 1 regulates the production of pro-inflammatory cytokines and anti-inflammatory cytokines and play an immunomodulatory role[1].
CAS Number
1817633-49-0
UNSPSC
12352005
Target
Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cb2r-agonist-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(NCCCCC)C=CC=C1)NC23CC4CC(C3)CC(C2)C4
Molecular Formula
C22H32N2O
Molecular Weight
340.50
References & Citations
[1]Graziano G, et al. N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R) . Eur J Med Chem. 2023 Feb 15;248:115109.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CB2

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