CB2R agonist 1

• Description :

  CB2R agonist 1 is a selective ligand of cannabinoid receptor subtype 2 (CB2R) with an EC50 value of 0.56 µM. CB2R agonist 1 has high affinity and excellent selectivity for human CB2R and CB1R respectively. CB2R agonist 1 regulates the production of pro-inflammatory cytokines and anti-inflammatory cytokines and play an immunomodulatory role[1].

• UNSPSC :

  12352005

• Target :

  Cannabinoid Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/cb2r-agonist-1.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=C(NCCCCC)C=CC=C1)NC23CC4CC(C3)CC(C2)C4

• Molecular Formula :

  C22H32N2O

• Molecular Weight :

  340.50

• References & Citations :

  [1]Graziano G, et al. N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R) . Eur J Med Chem. 2023 Feb 15;248:115109.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CB2

• CAS Number :

  [1817633-49-0]