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BMS-641988

CAT: 0804-HY-13607-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13607-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMS-641988 (compound 23) is an oral active nonsteroidal androgen receptor antagonist with the Ki of 1.7 nM. BMS-641988 shows anticancer activity[1].
CAS Number
1093276-09-5
UNSPSC
12352005
Target
Androgen Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bms-641988.html
Purity
99.70
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@]3([H])[C@](C(N(C4=CC(C(F)(F)F)=C(C=C4)C#N)C3=O)=O)([H])[C@@](O1)([C@@H](C2)NS(CC)(=O)=O)C
Molecular Formula
C20H20F3N3O5S
Molecular Weight
471.45
References & Citations
[1]Balog A, et al. Discovery of BMS-641988, a Novel Androgen Receptor Antagonist for the Treatment of Prostate Cancer. ACS Med Chem Lett. 2015;6 (8) :908-912. Published 2015 Jun 19.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1

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