TD-106

• UNSPSC Description:

  TD-106 is a cereblon (CRBN) modulator, which can be used for targeted protein degradation. BRD4 PROTACs with TD-106 induce BRD4 degradation[1].

• Target Antigen:

  Ligands for E3 Ligase

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/TD-106.html

• Purity:

  98.67

• Solubility:

  DMSO : ≥ 125 mg/mL

• Smiles:

  NC1=CC=CC(N=NN2C3CCC(NC3=O)=O)=C1C2=O

• Molecular Weight:

  273.252

• References & Citations:

  [1]Kim SA, et al. A novel cereblon modulator for targeted protein degradation. Eur J Med Chem. 2019 Mar 15;166:65-74.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported

• CAS Number:

  2250288-69-6