TD-6450

• Description:

  TD-6450 (Compound 51) is an orally active HCV 1A inhibitor. TD-6450 inhibits the pan-genotypic nonstructural protein 5A (NS5A) . TD-6450 can be used for research on diseases such as hepatitis[1].

• UNSPSC:

  12352005

• Target:

  HCV

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Smiles:

  COC(N[C@@H](C(C)C)C(N1[C@H](C(N2)=NC=C2C(C=C3)=CC=C3C4=C(OC(F)(F)F)C=C(NC(C5=CN=C(C=C5)N6C[C@@H](N(C[C@H]6C)C(NC)=O)C)=O)C=C4)CCC1)=O)=O

• Molecular Formula:

  C41H48F3N9O6

• Molecular Weight:

  819.87

• References & Citations:

  [1]Belema M, et al. Discovery and development of hepatitis C virus NS5A replication complex inhibitors. J Med Chem. 2014 Mar 13;57 (5) :1643-72. |[2]Carucci M, et al. Safe drugs with high potential to block malaria transmission revealed by a spleen-mimetic screening. Nat Commun. 2023 Apr 7;14 (1) :1951.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1374883-22-3]