TD-6450

• Description :

  TD-6450 (Compound 51) is an orally active HCV 1A inhibitor. TD-6450 inhibits the pan-genotypic nonstructural protein 5A (NS5A) . TD-6450 can be used for research on diseases such as hepatitis[1].

• UNSPSC :

  12352005

• Target :

  HCV

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Smiles :

  COC(N[C@@H](C(C)C)C(N1[C@H](C(N2)=NC=C2C(C=C3)=CC=C3C4=C(OC(F)(F)F)C=C(NC(C5=CN=C(C=C5)N6C[C@@H](N(C[C@H]6C)C(NC)=O)C)=O)C=C4)CCC1)=O)=O

• Molecular Formula :

  C41H48F3N9O6

• Molecular Weight :

  819.87

• References & Citations :

  [1]Belema M, et al. Discovery and development of hepatitis C virus NS5A replication complex inhibitors. J Med Chem. 2014 Mar 13;57 (5) :1643-72. |[2]Carucci M, et al. Safe drugs with high potential to block malaria transmission revealed by a spleen-mimetic screening. Nat Commun. 2023 Apr 7;14 (1) :1951.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1374883-22-3]