DMP 904

CAT: 0804-HY-12132Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-12132Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
DMP 904 is a noncompetitive full corticotropin-releasing factor receptor (CRFR) antagonist. DMP 904 can inhibit CRF-stimulated adenylate cyclase activity and ACTH release. DMP 904 exhibits anti-depressant and anti-anxiety activity[1][2].
CAS Number
[202579-74-6]
UNSPSC
12352005
Target
Adenylate Cyclase; CRFR
Related Pathways
GPCR/G Protein
Field of Research
Neurological Disease
Smiles
CC1=NC2=C(C3=CC=C(OC)C=C3C)C(C)=NN2C(NC(CC)CC)=C1
Molecular Formula
C21H28N4O
Molecular Weight
352.47
References & Citations
[1]Li YW, et al. The pharmacology of DMP696 and DMP904, non-peptidergic CRF1 receptor antagonists. CNS Drug Rev. 2005 Spring;11 (1) :21-52.|[2]Nielsen DM, et al. Antidepressant-like activity of corticotropin-releasing factor type-1 receptor antagonists in mice. Eur J Pharmacol. 2004 Sep 19;499 (1-2) :135-46.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-U00128-01PPA-904
HY-117747DMP 323
HY-108590-01DMP-543
HY-12131-01DMP 696
HY-75957-01DMP 777
HY-19281DMP-851
HY-125615DMP 728 (methanesulfonate)
HY-167848DMP-728 (free base)
HY-P70105-01DMP-1, Human (HEK293, His)
HY-123421UK-9040

Alternative Products

CatalogName
MBS1412277-01Recombinant Rat Protein PRRC1 (Prrc1)
MBS1412275-01Recombinant Danio rerio Mediator of RNA polymerase II transcription subunit 30 (med30)
MBS1412271-01Recombinant Yersinia pestis bv. Antiqua Iron-sulfur cluster repair protein YtfE (ytfE)
MBS1407862-01Recombinant Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai Holo-[acyl-carrier-protein] synthase (acpS)
MBS1412255-01Recombinant Streptococcus pyogenes serotype M6 30S ribosomal protein S20 (rpsT)
MBS1407861-01Recombinant Sulfolobus acidocaldarius CCA-adding enzyme (cca)
MBS1412252-01Recombinant Staphylococcus aureus tRNA modification GTPase MnmE (mnmE)
MBS1412248-01Recombinant Neurospora crassa Adenylate kinase 1 (adk-1)
MBS1412246-01Recombinant Phalaenopsis aphrodite subsp. formosana DNA-directed RNA polymerase subunit alpha (rpoA)
MBS1412244-01Recombinant Nitrosomonas europaea Lipoprotein-releasing system ATP-binding protein LolD (lolD)

Popular Products