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DMP 696

CAT: 0804-HY-12131-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-12131-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DMP 696 is a selective corticotropin-releasing hormone receptor 1 (CRHR1) antagonist, used for the treatment of anxiety and depression.
CAS Number
[202578-52-7]
UNSPSC
12352005
Target
CRFR
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/DMP_696.html
Purity
99.03
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=NN2C(N=C(C)N=C2NC(COC)COC)=C1C3=CC=C(Cl)C=C3Cl
Molecular Formula
C18H21Cl2N5O2
Molecular Weight
410.30
References & Citations
[1]Thoeringer CK, et al. Consolidation of remote fear memories involves Corticotropin-Releasing Hormone (CRH) receptor type 1-mediated enhancement of AMPA receptor GluR1 signaling in the dentate gyrus. Neuropsychopharmacology. 2012 Feb;37 (3) :787-96.|[2]Hubbard DT, et al. Activation of basolateral amygdala corticotropin-releasing factor 1 receptors modulates the consolidation of contextual fear. Neuroscience. 2007 Dec 19;150 (4) :818-28. Epub 2007 Oct 5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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