DMP 696

• UNSPSC Description:

  DMP 696 is a selective corticotropin-releasing hormone receptor 1 (CRHR1) antagonist, used for the treatment of anxiety and depression.

• Target Antigen:

  CRFR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Endocrinology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/DMP_696.html

• Purity:

  99.03

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC1=NN2C(N=C(C)N=C2NC(COC)COC)=C1C3=CC=C(Cl)C=C3Cl

• Molecular Weight:

  410.30

• References & Citations:

  [1]Thoeringer CK, et al. Consolidation of remote fear memories involves Corticotropin-Releasing Hormone (CRH) receptor type 1-mediated enhancement of AMPA receptor GluR1 signaling in the dentate gyrus. Neuropsychopharmacology. 2012 Feb;37(3):787-96.|[2]Hubbard DT, et al. Activation of basolateral amygdala corticotropin-releasing factor 1 receptors modulates the consolidation of contextual fear. Neuroscience. 2007 Dec 19;150(4):818-28. Epub 2007 Oct 5.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  202578-52-7