DMP-543

CAT: 0804-HY-108590-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-108590-01Size:5 mg
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Description
DMP-543 (XR-543) is a KV7 channel blocker, also acts as a potent neurotransmitter release enhancer[1][2].
CAS Number
[160588-45-4]
Product Name Alternative
XR-543
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dmp-543.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C2=C(C=CC=C2)C(CC3=CC(F)=NC=C3)(CC4=CC(F)=NC=C4)C5=CC=CC=C15
Molecular Formula
C26H18F2N2O
Molecular Weight
412.43
Precautions
H315, H319, H335
References & Citations
[1]Ipavec V, et al. KV7 channels regulate muscle tone and nonadrenergic noncholinergic relaxation of the rat gastric fundus. Pharmacol Res. 2011 Oct;64 (4) :397-409.|[2]Zaczek R, et al. Two new potent neurotransmitter release enhancers, 10,10-bis (4-pyridinylmethyl) -9 (10H) -anthracenone and 10,10-bis (2-fluoro-4-pyridinylmethyl) -9 (10H) -anthracenone: comparison to linopirdine. J Pharmacol Exp Ther. 1998 May;285 (2) :724-30.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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Alternative Products

CatalogName
447586-01DMP 543
BUP05715-01DMP-543
A19991-2DMP-543 2mg
A19991-10DMP-543 10mg
A19991-50DMP-543 50mg
A19991-5DMP-543 5mg
A19991-100DMP-543 100mg
A19991-1DMP-543 1mg
A19991-25DMP-543 25mg
A19991-10mM-DDMP-543 10mM * 1mL in DMSO

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