Products for Research Use Only

RIPK1-IN-38

CAT: 0013-GTR19275479-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19275479-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
RIPK1-IN-38 is an orally active inhibitor of RIPK1 with an IC50 of 27 nM. It effectively suppresses the phosphorylation of RIPK1 and its downstream targets RIPK3 and MLKL. Demonstrating anti-necroptosis activity, RIPK1-IN-38 exhibits excellent anti-inflammatory properties in SIRS and GVHD models, making it suitable for research into inflammation and immune-related diseases.
CAS Number
3092834-30-2
Smiles
C (N[C@@H] (C) C1=CC=C (F) C=C1) (=O) C2=C3N (N=C2) C=CC (=C3) C=4C=C5C (=CC4) N=C (NC (=O) C6CC6) S5
Molecular Formula
C27H22FN5O2S
Molecular Weight
499.56
Storage Conditions
-20°C
Notes
For research use only.