STING agonist-49

• Description:

  STING agonist-49 (Compound 1) is a STING agonist and can be used as a payload for ADCs. STING agonist-49 can be applied in lung cancer research[1].

• UNSPSC:

  12352005

• Target:

  ADC Payload; STING

• Related Pathways:

  Antibody-drug Conjugate/ADC Related; Immunology/Inflammation

• Field of Research:

  Cancer

• Smiles:

  O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CC(OC)=C3N2C/C=C/CN4C(NC(C5=CC(C)=NN5CC)=O)=NC6=C4C(OCCCNC)=CC(C(N)=O)=C6

• Molecular Formula:

  C39H47N13O6

• Molecular Weight:

  793.87

• References & Citations:

  [1]Gruber DR, et al. Targeted delivery of a potent STING agonist payload via an antibody drug conjugate drives robust antitumor activity in preclinical models. Mol Cancer Ther. 2025 Oct 29.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2138299-66-6