USP1 antibody

CAT: 0710-FNab09302Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab09302Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2 (PubMed:15694335) . Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA (PubMed:16531995) . Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:18082604, PubMed:26388029) .
Synonyms
Ubiquitin carboxyl-terminal hydrolase 1|Deubiquitinating enzyme 1 (hUBP) |Ubiquitin thioesterase 1|Ubiquitin-specific-processing protease 1|Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment|USP1
Gene ID
7398
UniProt
O94782
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Ubiquitin specific peptidase 1
Target
USP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IHC: 1:20-1:200; IP: 1:200-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
100 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP

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