BChE-IN-45

• Description:

  BChE-IN-45 is a competitive (cholinesterase) dual acting inhibitor (Ki = 11.13 μM) . BChE-IN-45 has an IC50 of 13.8 μM for BChE and 35.63 μM for AChE. BChE-IN-45 can be used for research on Alzheimer's disease[1].

• UNSPSC:

  12352005

• Target:

  Cholinesterase (ChE)

• Related Pathways:

  Neuronal Signaling

• Field of Research:

  Neurological Disease

• Smiles:

  CC1=CC=C(COC2=CC=C(C3C(C(CC(C)(C)C4)=O)=C4NC(CC(C)(C)C5)=C3C5=O)C=C2OC)C=C1

• Molecular Formula:

  C32H37NO4

• Molecular Weight:

  499.64

• References & Citations:

  [1]Najafi Z, et al. Novel Hexahydroacridine‐1, 8‐diones as Cholinesterase Inhibitors: Design, Synthesis, Molecular Docking, and Molecular Dynamics Simulation[J]. ChemistrySelect, 2025, 10 (39) : e00879.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  AChE; BChE

• CAS Number:

  425611-45-6