HDAC-IN-93

• Description:

  HDAC-IN-93 is a HDAC inhibitor with promising total pan-HDAC inhibitory activity. HDAC-IN-93 demonstrates significant broad-spectrum antiproliferative activity across various cancer cell lines. HDAC-IN-93 induces cell apoptosis along with necrosis. HDAC-IN-93 can be used for the studies of prostate cancer and breast cancer[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis; Bcl-2 Family; Caspase; HDAC

• Related Pathways:

  Apoptosis; Cell Cycle/DNA Damage; Epigenetics

• Field of Research:

  Cancer

• Smiles:

  N/C(C(C=C1)=CC=C1/C=C/C2=CC(C3=CC=CC=C3O2)=O)=N\O

• Molecular Formula:

  C18H14N2O3

• Molecular Weight:

  306.32

• References & Citations:

  [1]Ashraf R, et al. Design and synthesis of novel Hydroxamate and non-Hydroxamate HDAC inhibitors based on Chromone and Quinazolone scaffolds. Bioorg Chem. 2025 Jul 1;161:108514.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Bax; Bcl-2; Caspase 3; HDAC6; HDAC7; HDAC8