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CDD-2212

CAT: 0804-HY-176885ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-176885ASize:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDD-2212 is a STK33 inhibitor, with a Kd of 1.9 nM and an IC50 of 999 nM. CDD-2212 has relatively weak inhibitory effects on off-target kinases, with IC50 values of 3223 nM for CLK1, 1555 nM for CLK2, 5884 nM for CLK4, and 1093 nM for RET. CDD-2212 can be used for the study of contraception[1].
CAS Number
[3086535-52-3]
Target
RET; STK33
Related Pathways
Cell Cycle/DNA Damage; Protein Tyrosine Kinase/RTK
Field of Research
Others
Smiles
O=C(N1C[C@H](CC1)N(C)C)C2=CC=C3C(C(C#CC4=C(C5=CC=CC=C5)C=CC=C4)=NN3)=C2
Molecular Formula
C28H26N4O
Molecular Weight
434.53
References & Citations
[1]Ku AF, et al. Reversible male contraception by targeted inhibition of serine/threonine kinase 33. Science. 2024 May 24;384 (6698) :885-890.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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