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Antimalarial agent 51

CAT: 0804-HY-176223Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-176223Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antimalarial agent 51 (Compound 2) is an orally active antimalarial compound. Antimalarial agent 51 blocks nutrient uptake by Plasmodium by inhibiting the plasmodium surface anion channel (PSAC) . Antimalarial agent 51 significantly inhibits the growth of Plasmodium under nutrient-restricted conditions. Combination of antimalarial agent 51 with the residual transport inhibitor PRT-2 can enhance the antimalarial effect. Antimalarial agent 51 can be used in the study of malaria targeting the PSAC channel[1].
UNSPSC
12352005
Target
Parasite
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(N(C1)CC[C@@]21C[C@@H](NC3=NC=NC=C3)C2)C4=CC5=C(C=CC=C5)N4
Molecular Formula
C20H21N5O
Molecular Weight
347.41
References & Citations
[1]Molina I, et al. The critical role of PSAC channel in malaria parasite survival is driven home by phenotypic screening under relevant nutrient levels. Cell Chem Biol. 2025 May 21:S2451-9456 (25) 00136-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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